Bile Acids

Bile acids are synthesized in the liver and play a vital physiological role. They are not only detergent of dietary lipids and nutrients, but also important hormones or nutrient signaling molecules in metabolic regulation process. Because of their unique amphipathic configuration, conventionally BAs were thought to have only the detergent properties for a long time, which contributes to digestion of dietary lipids, elimination of cholesterol and absorption of fat-soluble vitamins. However, studies have shown that Bile acids can act as as hormones or nutrient signaling molecules. Emerging evidence indicates that Bile acids not only regulate their own synthesis and enterohepatic recirculation, but also the regulation of glucose, lipoprotein and lipid metabolism, thyroid hormone signaling, cellular immunity, energy expenditure and inflammatory responses. The most common, cholic acid and chenodeoxycholic acid, are called primary bile acids. Recent studies have shown that bile acids are involvement in various cancers and diseases such as  Parkinson’s and Alzheimer’s and liver diseases.

Bile Acids Measured in Steroidomics Lab Test

1. Cholic acid (CA)

2. Deoxycholic acid (DCA)

3. Chenodeoxycholic acid (CDCA)

4. Lithocholic acid (LCA)

5. Ursodeoxycholic acid (UDCA)

We can measure many other bile acids listed below, please contact us

Murocholic acid
Hyodeoxycholic acid
Allolithocholic acid
Taurocholanic acid
Taurohyodeoxycholic acid
Taurochenodeoxycholic acid
Desoxycholic acid
Taurolithocholic acid
Glycolithocholic acid
6-Keto-allolithocholic acid
Glycodeoxycholic acid
Glycochenodeoxycholic acid
Tauroursodeoxycholic acid
Taurodeoxycholic acid
Glycodeoxycholic acid
a-Muricholic acid
b-Muricholic acid
Tauro-b-Muricholic acid
Taurocholic acid
Taurodehydrocholic acid
Glycodehydrocholic acid

Test Method

Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)