Toxic DNA Adducts

Estrogens are implicated in the development and/or progression of many diseases, such as breast cancer, ovarian cancer, prostate cancer, endometrial cancer, osteoporosis, neurodegenerative diseases, cardiovascular disease and obesity. It is suggested that toxic estrogen metabolites that are formed by oxidative stress form DNA adducts. These DNA adducts can lead to many diseases.

DNA adducts Measured in Steroidomics Lab Test

1. Estrogen-DNA adducts

2. Catecholestrogen-DNA adducts

Test Method

Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)